Tetrahydrofuran → [1-(4-chloro-benzyl)-1H-indol-3-yl]-[4-pyridin-2-yl-5-(toluene-4-sulfonyl)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-methanol
Reaction equation
[CH2:60]1[O:61][CH2:62][CH2:63][CH2:64]1.[CH3:30][CH2:31][CH2:32][CH2:33][Li:34].[CH3:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40].[Cl:41][c:42]1[cH:43][cH:44][c:45]([CH2:46][n:47]2[cH:48][c:49]([CH:56]=[O:57])[c:50]3[cH:51][cH:52][cH:53][cH:54][c:55]23)[cH:58][cH:59]1.[c:1]1([CH3:29])[cH:2][cH:3][c:4]([S:7](=[O:8])(=[O:9])[c:10]2[c:11](-[c:23]3[n:24][cH:25][cH:26][cH:27][cH:28]3)[n:12][cH:13][n:14]2[CH2:15][O:16][CH2:17][CH2:18][Si:19]([CH3:20])([CH3:21])[CH3:22])[cH:5][cH:6]1>>[c:1]1([CH3:29])[cH:2][cH:3][c:4]([S:7](=[O:8])(=[O:9])[c:10]2[c:11](-[c:23]3[n:24][cH:25][cH:26][cH:27][cH:28]3)[n:12][c:13]([CH:56]([c:49]3[cH:48][n:47]([CH2:46][c:45]4[cH:44][cH:43][c:42]([Cl:41])[cH:59][cH:58]4)[c:55]4[c:50]3[cH:51][cH:52][cH:53][cH:54]4)[OH:57])[n:14]2[CH2:15][O:16][CH2:17][CH2:18][Si:19]([CH3:20])([CH3:21])[CH3:22])[cH:5][cH:6]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-c93aa14608104793b4a9f73c5dc49fbd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…