Hydrochloric Acid → 2-[4-Chloro-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]-1-{4-[4-(2-phenylethyl)-1,3-thiazol-2-yl]piperidin-1-yl}propan-1-one
Reaction equation
[Cl:48][c:49]1[c:50]([C:60]([F:61])([F:62])[F:63])[n:51][n:52]([CH:55]([C:56](=[O:57])[OH:58])[CH3:59])[c:53]1[CH3:54].[ClH:1].[c:21]1([CH2:22][CH2:23][c:24]2[n:25][c:26]([CH:27]3[CH2:28][CH2:29][N:30]([C:31](=[O:32])[CH2:33][c:34]4[cH:35][cH:36][s:37][cH:38]4)[CH2:39][CH2:40]3)[s:41][cH:42]2)[cH:43][cH:44][cH:45][cH:46][cH:47]1.[c:2]1([CH2:8][CH2:9][c:10]2[n:11][c:12]([CH:15]3[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]3)[s:13][cH:14]2)[cH:3][cH:4][cH:5][cH:6][cH:7]1>>[c:2]1([CH2:8][CH2:9][c:10]2[n:11][c:12]([CH:15]3[CH2:16][CH2:17][N:18]([C:56]([CH:55]([n:52]4[n:51][c:50]([C:60]([F:61])([F:62])[F:63])[c:49]([Cl:48])[c:53]4[CH3:54])[CH3:59])=[O:57])[CH2:19][CH2:20]3)[s:13][cH:14]2)[cH:3][cH:4][cH:5][cH:6][cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-6fa8e9f5170847e3bb5e9dc554b1c274
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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