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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2160353Generated: November 1, 2026

Bicarbonate Ion → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[6-(1H-pyrazol-5-yl)pyridazin-3-yl]amino}thiophene-3-carboxamide

https://huagongshe.com/reaction/2160353

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantTetrahydrofuranHCID 8028—
Reactant2-[(6-Chloropyridazin-3-yl)amino]-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59526128—
ReactantHCID 178514837HCID 178514837—
Product5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[6-(1H-pyrazol-5-yl)pyridazin-3-yl]amino}thiophene-3-carboxamideHCID 59526217—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-b426b8a5b2d7494aa57d43dd13a32690
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)