Methanol → Methyl {6-[2-(cis-4-hydroxycyclohexyl)-1-oxo-2,8-diazaspiro[4.5]dec-8-yl]-5-methylpyridin-3-yl}carbamate
Reaction equation
[CH3:41][C:42]#[N:43].[CH3:44][OH:45].[CH:32]([N:33]([CH2:34][CH3:35])[CH:36]([CH3:37])[CH3:38])([CH3:39])[CH3:40].[Cl:1][C:2](=[O:3])[O:4][CH3:5].[NH2:6][c:7]1[cH:8][c:9]([CH3:31])[c:10]([N:13]2[CH2:14][CH2:15][C:16]3([CH2:17][CH2:18][N:19]([CH:22]4[CH2:23][CH2:24][CH:25]([OH:28])[CH2:26][CH2:27]4)[C:20]3=[O:21])[CH2:29][CH2:30]2)[n:11][cH:12]1>>[C:2](=[O:3])([O:4][CH3:5])[NH:6][c:7]1[cH:8][c:9]([CH3:31])[c:10]([N:13]2[CH2:14][CH2:15][C:16]3([CH2:17][CH2:18][N:19]([CH:22]4[CH2:23][CH2:24][CH:25]([OH:28])[CH2:26][CH2:27]4)[C:20]3=[O:21])[CH2:29][CH2:30]2)[n:11][cH:12]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-e7d7e11129a6415b91db4612d71005a2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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