Toluene → 3-[3-[tert-butyl(dimethyl)silyl]oxyazetidin-1-yl]-N-(5-cyano-2-pyridinyl)-2-hydroxypropanamide
Reaction equation
[C:14]([CH3:15])([CH3:16])([CH3:17])[Si:18]([O:19][CH:20]1[CH2:21][N:22]([CH2:24][CH:25]([C:26](=[O:27])[O:28][CH3:29])[OH:30])[CH2:23]1)([CH3:31])[CH3:32].[CH3:1][Al:2]([CH3:3])[CH3:4].[CH3:33][c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1.[NH2:5][c:6]1[n:7][cH:8][c:9]([C:10]#[N:11])[cH:12][cH:13]1>>[NH:5]([c:6]1[n:7][cH:8][c:9]([C:10]#[N:11])[cH:12][cH:13]1)[C:26]([CH:25]([CH2:24][N:22]1[CH2:21][CH:20]([O:19][Si:18]([C:14]([CH3:15])([CH3:16])[CH3:17])([CH3:31])[CH3:32])[CH2:23]1)[OH:30])=[O:27]Participants
5
Sources & evidence
- ORD record
- ord-5b40df8ce1b84325898d03e2d810a4c6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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