Dimethylformamide → 2-Phenyl-ethanesulfonic acid [6-chloro-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yl]-amide

HRID 2160988Notes

Reaction equation

HRID 2160988 reaction equation
[Cl:1][c:2]1[n:3][c:4](-[c:18]2[cH:19][cH:20][n:21][cH:22][cH:23]2)[n:5][c:6]([Cl:17])[c:7]1[O:8][c:9]1[c:10]([O:15][CH3:16])[cH:11][cH:12][cH:13][cH:14]1.[K:24].[O:37]=[CH:38][N:39]([CH3:40])[CH3:41].[c:25]1([CH2:31][CH2:32][S:33](=[O:34])(=[O:35])[NH2:36])[cH:26][cH:27][cH:28][cH:29][cH:30]1>>[c:2]1([NH:36][S:33]([CH2:32][CH2:31][c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)(=[O:34])=[O:35])[n:3][c:4](-[c:18]2[cH:19][cH:20][n:21][cH:22][cH:23]2)[n:5][c:6]([Cl:17])[c:7]1[O:8][c:9]1[c:10]([O:15][CH3:16])[cH:11][cH:12][cH:13][cH:14]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 204808BenzeneethanesulfonamideHCID 5462222PotassiumHCID 111754584,6-Dichloro-5-(2-methoxyphenoxy)-2-(pyridin-4-YL)pyrimidine

Product 1

HCID 865924712-Phenyl-ethanesulfonic acid [6-chloro-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yl]-amide

Sources & evidence

ORD record
ord-646e33653ade4a068d5c64097f842048
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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