Acetate → Tert-butyl 2-[2-[3-phenylmethoxy-4-[1,1,4-trioxo-5-(2-trimethylsilylethyl)-1,2,5-thiadiazolidin-2-yl]phenyl]ethenyl]piperidine-1-carboxylate

HRID 2161161Notes

Reaction equation

HRID 2161161 reaction equation
[C:30]([CH3:31])([CH3:32])([CH3:33])[O:34][C:35](=[O:36])[N:37]1[CH:38]([CH:43]=[CH2:44])[CH2:39][CH2:40][CH2:41][CH2:42]1.[C:52]([P:53]([C:54]([CH3:55])([CH3:56])[CH3:57])[c:58]1[cH:59][cH:60][cH:61][cH:62][c:63]1-[c:64]1[cH:65][cH:66][cH:67][cH:68][c:69]1[P:70]([C:71]([CH3:72])([CH3:73])[CH3:74])[C:75]([CH3:76])([CH3:77])[CH3:78])([CH3:79])([CH3:80])[CH3:81].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([N:16]2[CH2:17][C:18](=[O:29])[N:19]([CH2:23][CH2:24][Si:25]([CH3:26])([CH3:27])[CH3:28])[S:20]2(=[O:21])=[O:22])[cH:11][cH:12][c:13]([I:15])[cH:14]1.[CH3:45][CH2:46][N:47]([CH2:48][CH3:49])[CH2:50][CH3:51].[CH3:82][C:83]#[N:84].[O-:86][C:87]([CH3:88])=[O:89].[O-:90][C:91]([CH3:92])=[O:93].[Pd+2:85]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([N:16]2[CH2:17][C:18](=[O:29])[N:19]([CH2:23][CH2:24][Si:25]([CH3:26])([CH3:27])[CH3:28])[S:20]2(=[O:21])=[O:22])[cH:11][cH:12][c:13]([CH:44]=[CH:43][CH:38]2[N:37]([C:35]([O:34][C:30]([CH3:31])([CH3:32])[CH3:33])=[O:36])[CH2:42][CH2:41][CH2:40][CH2:39]2)[cH:14]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 6342AcetonitrileHCID 8471TriethylamineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 14898394tert-butyl 2-Vinylpiperidine-1-carboxylateHCID 534414812,2'-Bis(DI-tert-butylphosphino)biphenylHCID 667569375-(2-Benzyloxy-4-iodophenyl)-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one

Product 1

HCID 68838477Tert-butyl 2-[2-[3-phenylmethoxy-4-[1,1,4-trioxo-5-(2-trimethylsilylethyl)-1,2,5-thiadiazolidin-2-yl]phenyl]ethenyl]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-5b20855c73b94a61aa336150704405cb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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