Dimethylformamide → tert-Butyl 4-(cyclopropylcarbamoyl)piperidine-1-carboxylate

HRID 2161208Notes

Reaction equation

HRID 2161208 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14](=[O:15])[OH:16])[CH2:12][CH2:13]1.[CH:17]1([NH2:20])[CH2:18][CH2:19]1.[O:45]=[CH:46][N:47]([CH3:48])[CH3:49].[P-:21]([F:22])([F:23])([F:24])([F:25])([F:26])[F:27].[n:28]1([O:29][C:30]([N:31]([CH3:32])[CH3:33])=[N+:34]([CH3:35])[CH3:36])[c:37]2[n:38][cH:39][cH:40][cH:41][c:42]2[n:43][n:44]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14](=[O:16])[NH:20][CH:17]2[CH2:18][CH2:19]2)[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 69828CyclopropylamineHCID 3928711-(tert-Butoxycarbonyl)-4-piperidinecarboxylic acidHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminium

Product 1

HCID 24688815tert-Butyl 4-(cyclopropylcarbamoyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-df4fb0f1b0fc4cab877bf692b52cbac6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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