Ammonium → tert-Butyl 4-amino-4-cyanopiperidine-1-carboxylate

HRID 2161596Notes

Reaction equation

HRID 2161596 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]1.[CH3:20][OH:21].[Cl-:15].[NH4+:16].[Na:17][C:18]#[N:19]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([NH2:16])([C:18]#[N:19])[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 223AmmoniumHCID 312ChlorideHCID 887MethanolHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylateHCID 178511850HCID 178511850, compound

Product 1

HCID 22091429tert-Butyl 4-amino-4-cyanopiperidine-1-carboxylate

Sources & evidence

ORD record
ord-0e6ffd5b48c14c86936bef9150738951
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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