Potassium Cation → Methyl 2-amino-5-cyclopropylbenzoate

HRID 2162125Notes

Reaction equation

HRID 2162125 reaction equation
[CH3:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1.[CH:13]1([B:16]([OH:17])[OH:18])[CH2:14][CH2:15]1.[K+:24].[K+:25].[K+:26].[NH2:1][c:2]1[c:3]([C:4](=[O:5])[O:6][CH3:7])[cH:8][c:9]([Br:12])[cH:10][cH:11]1.[OH2:34].[P:19]([O-:20])([O-:21])([O-:22])=[O:23]>>[NH2:1][c:2]1[c:3]([C:4](=[O:5])[O:6][CH3:7])[cH:8][c:9]([CH:13]2[CH2:14][CH2:15]2)[cH:10][cH:11]1

Participants

7

Reactant 6

HCID 813Potassium Cation3×HCID 962WaterHCID 1061PhosphateHCID 1140TolueneHCID 736224Methyl 2-amino-5-bromobenzoateHCID 2760897Cyclopropylboronic acid

Product 1

HCID 13052309Methyl 2-amino-5-cyclopropylbenzoate

Sources & evidence

ORD record
ord-cfa9a20f0983445ba738083ec922b88d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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