Dichloromethane → 5-bromo-N-[1-(2-methylpropylsulfonyl)piperidin-3-yl]-2-methylsulfanylpyrimidin-4-amine

HRID 2162217Notes

Reaction equation

HRID 2162217 reaction equation
[Br:1][c:2]1[c:3]([NH:10][CH:11]2[CH2:12][NH:13][CH2:14][CH2:15][CH2:16]2)[n:4][c:5]([S:8][CH3:9])[n:6][cH:7]1.[CH3:26][CH:27]([CH2:28][S:29](=[O:30])(=[O:31])[Cl:32])[CH3:33].[CH:17]([N:18]([CH:19]([CH3:20])[CH3:21])[CH2:22][CH3:23])([CH3:24])[CH3:25].[Cl:34][CH2:35][Cl:36]>>[Br:1][c:2]1[c:3]([NH:10][CH:11]2[CH2:12][N:13]([S:29]([CH2:28][CH:27]([CH3:26])[CH3:33])(=[O:30])=[O:31])[CH2:14][CH2:15][CH2:16]2)[n:4][c:5]([S:8][CH3:9])[n:6][cH:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 81531DiisopropylethylamineHCID 1822361-Propanesulfonyl chloride, 2-methyl-HCID 698100765-bromo-2-methylsulfanyl-N-piperidin-3-ylpyrimidin-4-amine

Product 1

HCID 698127465-bromo-N-[1-(2-methylpropylsulfonyl)piperidin-3-yl]-2-methylsulfanylpyrimidin-4-amine

Sources & evidence

ORD record
ord-531a9c81f73f4158afa5373aefd400e1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…