Chloride → (RS)-Clopidogrel

HRID 2162225Notes

Reaction equation

HRID 2162225 reaction equation
[CH3:21][c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1.[CH3:28][OH:29].[Cl-:30].[Cl-:31].[Cl-:32].[Cl-:33].[Cl:1][c:2]1[c:3]([CH:8]([C:9](=[O:10])[NH2:11])[N:12]2[CH2:13][c:14]3[c:15]([s:18][cH:19][cH:20]3)[CH2:16][CH2:17]2)[cH:4][cH:5][cH:6][cH:7]1.[Ti+4:34]>>[Cl:1][c:2]1[c:3]([CH:8]([C:9](=[O:10])[O:29][CH3:28])[N:12]2[CH2:13][c:14]3[c:15]([s:18][cH:19][cH:20]3)[CH2:16][CH2:17]2)[cH:4][cH:5][cH:6][cH:7]1

Participants

6

Reactant 5

HCID 312Chloride4×HCID 887MethanolHCID 1140TolueneHCID 114942Titanium cation (4+)HCID 113128242-Chlorophenyl-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetamide

Product 1

HCID 2806(RS)-Clopidogrel

Sources & evidence

ORD record
ord-b777f931c6534d5e9e961f8b727d1904
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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