Dichloromethane → 4-(1,4-Dioxa-spiro[4.5]dec-7-en-8-yl)benzonitrile

HRID 2162257Notes

Reaction equation

HRID 2162257 reaction equation
[CH2:32]([Cl:33])[Cl:34].[CH3:20][CH2:21][N:22]([CH2:23][CH3:24])[CH2:25][CH3:26].[OH:1][C:2]1([c:12]2[cH:13][cH:14][c:15]([C:16]#[N:17])[cH:18][cH:19]2)[CH2:3][CH2:4][C:5]2([O:6][CH2:7][CH2:8][O:9]2)[CH2:10][CH2:11]1.[S:27]([Cl:28])([CH3:29])(=[O:30])=[O:31]>>[C:2]1([c:12]2[cH:13][cH:14][c:15]([C:16]#[N:17])[cH:18][cH:19]2)=[CH:3][CH2:4][C:5]2([O:6][CH2:7][CH2:8][O:9]2)[CH2:10][CH2:11]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 150239054-(8-Hydroxy-1,4-dioxaspiro[4.5]decan-8-yl)benzonitrile

Product 1

HCID 299213354-(1,4-Dioxa-spiro[4.5]dec-7-en-8-yl)benzonitrile

Sources & evidence

ORD record
ord-9399f5c5549a4ef5b254ca9500e980c5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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