Toluene → Ethyl 4,4-difluoro-3-oxo-2-(piperidin-1-ylmethylidene)butyrate
Reaction equation
[CH3:20][CH2:21][N:22]([CH2:23][CH3:24])[CH2:25][CH3:26].[CH3:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1.[F:14][CH:15]([C:16](=[O:17])[F:18])[F:19].[N:1]1([CH:7]=[CH:8][C:9](=[O:10])[O:11][CH2:12][CH3:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1>>[N:1]1([CH:7]=[C:8]([C:9](=[O:10])[O:11][CH2:12][CH3:13])[C:16]([CH:15]([F:14])[F:19])=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
5
Sources & evidence
- ORD record
- ord-8190284972634f99863ee74e9c46c369
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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