Diisopropylamine → 6-(2,6-Diethyl-phenyl)-4-(3-methoxy-prop-1-ynyl)-2-methyl-nicotinic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([c:5]1[c:6]([CH3:22])[n:7][c:8](-[c:12]2[c:13]([CH2:20][CH3:21])[cH:14][cH:15][cH:16][c:17]2[CH2:18][CH3:19])[cH:9][c:10]1[Br:11])=[O:23].[CH2:24]([C:25]#[CH:26])[O:27][CH3:28].[CH:29]([NH:30][CH:31]([CH3:32])[CH3:33])([CH3:34])[CH3:35].[Cu:113]([I:114])[I:115].[cH:36]1[cH:37][cH:38][c:39]([P:40]([Pd:41]([P:42]([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)([c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)([P:61]([c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)([c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)[P:80]([c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)([c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)[c:93]2[cH:94][cH:95][cH:96][cH:97][cH:98]2)([c:99]2[cH:100][cH:101][cH:102][cH:103][cH:104]2)[c:105]2[cH:106][cH:107][cH:108][cH:109][cH:110]2)[cH:111][cH:112]1>>[CH2:1]([CH3:2])[O:3][C:4]([c:5]1[c:6]([CH3:22])[n:7][c:8](-[c:12]2[c:13]([CH2:20][CH3:21])[cH:14][cH:15][cH:16][c:17]2[CH2:18][CH3:19])[cH:9][c:10]1[C:26]#[C:25][CH2:24][O:27][CH3:28])=[O:23]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-2c7c1a2964a84a5e96b08144e87654df
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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