反应详情

A solution of the product of Example 32D in N,N-dimethylformamide (60 mL) was treated with bis-(p-nitrophenyl)carbonate (12.6 g, 1.2 equivalents) at 50° C. for 5 hrs. The solvents were evaporated, and the residue was partitioned between water and ethyl acetate. The organic layer was separated, washed with brine, dried over Na2SO4, filtered, and the solvents were evaporated, and the residue was purified using ethyl acetate:hexanes (2:1) to give 7.3 g (57%) of the title compound.

1. customThe solvents were evaporated
2. customthe residue was partitioned between water and ethyl acetate
3. customThe organic layer was separated
4. washwashed with brine
5. dry with materialdried over Na2SO4
6. filtrationfiltered
7. customthe solvents were evaporated
8. customthe residue was purified