Ethanol → 2-(2-Aminoethyl)-4,6-bis(4-fluorophenyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridine

HRID 2162800Notes

Reaction equation

HRID 2162800 reaction equation
[CH3:47][CH2:48][O:49][C:50]([CH3:51])=[O:52].[CH3:53][CH2:54][OH:55].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]3[c:10]([n:11][c:12](-[c:20]4[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]4)[c:13]2-[c:14]2[cH:15][cH:16][n:17][cH:18][cH:19]2)[n:27][n:28]([CH2:30][CH2:31][N:32]2[C:33](=[O:34])[c:35]4[cH:36][cH:37][cH:38][cH:39][c:40]4[C:41]2=[O:42])[cH:29]3)[cH:6][cH:7]1.[NH2:44][NH2:45].[OH2:43].[OH2:46]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]3[c:10]([n:11][c:12](-[c:20]4[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]4)[c:13]2-[c:14]2[cH:15][cH:16][n:17][cH:18][cH:19]2)[n:27][n:28]([CH2:30][CH2:31][NH2:32])[cH:29]3)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 702EthanolHCID 962Water2×HCID 8857Ethyl AcetateHCID 9321HydrazineHCID 670147764,6-Bis(4-fluorophenyl)-2-(2-phthalimidoethyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridine

Product 1

HCID 670135732-(2-Aminoethyl)-4,6-bis(4-fluorophenyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridine

Sources & evidence

ORD record
ord-effe47a600d94a36b32a8892becf57a3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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