1,2-Dimethoxyethane → 5-Chloro-4-methoxy-4'-trifluoromethyl-biphenyl-3-carboxylic acid methyl ester
Reaction equation
[CH3:14][O:15][C:16]([c:17]1[c:18]([O:25][CH3:26])[c:19]([Cl:24])[cH:20][c:21]([Br:23])[cH:22]1)=[O:27].[CH3:28][O:29][CH2:30][CH2:31][O:32][CH3:33].[CH3:34][CH2:35][O:36][C:37]([CH3:38])=[O:39].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([B:9]([OH:10])[OH:11])[cH:7][cH:8]1)([F:12])[F:13].[cH:40]1[cH:41][cH:42][c:43]([P:44]([Pd:45]([P:46]([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)([c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)([P:65]([c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)([c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)[c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)[P:84]([c:85]2[cH:86][cH:87][cH:88][cH:89][cH:90]2)([c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)[c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)([c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)[c:109]2[cH:110][cH:111][cH:112][cH:113][cH:114]2)[cH:115][cH:116]1>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:21]2[cH:20][c:19]([Cl:24])[c:18]([O:25][CH3:26])[c:17]([C:16]([O:15][CH3:14])=[O:27])[cH:22]2)[cH:7][cH:8]1)([F:12])[F:13]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-9f395a443a85468b9ff161ee26f7d9e9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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