反应详情

温度

100 °C

A mixture of 3-pyridinesulfonic acid (1.0 g, 6.3 mmol), phosphorous pentachloride (1.6 g, 1.2 mmol), and phosphorous oxychloride (2.0 mL, 3.3 mmol) was combined and stirred at 100° C. for 18 h. The reaction was cooled to 25° C., diluted with CHCl3, and bubbled with HCl gas. The resulting precipitate was collected by filtration, washed with CHCl3, and dried in vacuo to yield 1.12 g of the title compound (84%).

1. temperatureThe reaction was cooled to 25° C.
2. custombubbled with HCl gas
3. filtrationThe resulting precipitate was collected by filtration
4. washwashed with CHCl3
5. customdried in vacuo