Ethanol → sodium 8-(3-[2-t-butylphenoxy]-2-hydroxypropoxy)-4-oxo-4H-1-benzopyran-2-carboxylate sesquihydrate

HRID 2163387Notes

Reaction equation

HRID 2163387 reaction equation
[C:1]([C:5]1[CH:30]=[CH:29][CH:28]=[CH:27][C:6]=1[O:7][CH2:8][CH:9]([OH:26])[CH2:10][O:11][C:12]1[C:21]2[O:20][C:19]([C:22]([OH:24])=[O:23])=[CH:18][C:17](=[O:25])[C:16]=2[CH:15]=[CH:14][CH:13]=1)([CH3:4])([CH3:3])[CH3:2].C([OH:33])C.C(=O)(O)[O-:35].[Na+:38]>O>[OH2:7].[C:1]([C:5]1[CH:30]=[CH:29][CH:28]=[CH:27][C:6]=1[O:7][CH2:8][CH:9]([OH:26])[CH2:10][O:11][C:12]1[C:21]2[O:20][C:19]([C:22]([O-:24])=[O:23])=[CH:18][C:17](=[O:25])[C:16]=2[CH:15]=[CH:14][CH:13]=1)([CH3:4])([CH3:2])[CH3:3].[Na+:38].[OH2:33].[OH2:35].[Na+:38].[C:1]([C:5]1[CH:30]=[CH:29][CH:28]=[CH:27][C:6]=1[O:7][CH2:8][CH:9]([OH:26])[CH2:10][O:11][C:12]1[C:21]2[O:20][C:19]([C:22]([O-:24])=[O:23])=[CH:18][C:17](=[O:25])[C:16]=2[CH:15]=[CH:14][CH:13]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

5

Reactant 3

HCID 702EthanolHCID 516892Sodium BicarbonateHCID 130909888-(3-[2-t-butylphenoxy]-2-hydroxypropoxy)-4-oxo-4H-1-benzopyran-2-carboxylic acid

Product 1

HCID 131710631sodium 8-(3-[2-t-butylphenoxy]-2-hydroxypropoxy)-4-oxo-4H-1-benzopyran-2-carboxylate sesquihydrate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a hot solution of 4.328 parts of 8-(3- 2-t-butylphenoxy -2-hydroxypropoxy)-4-oxo-4H-1-benzopyran-2-carboxylic acid in 250 parts of ethanol was added a solution of 0.882 parts of sodium bicarbonate in 50 parts of water. The resulting solution was filtered and allowed to cool to give 4.0 parts of sodium 8-(3-[2-t-butylphenoxy]-2-hydroxypropoxy)-4-oxo-4H-1-benzopyran-2-carboxylate sesquihydrate after collecting and drying over phosphorus pentoxide.

Workup

  1. filtrationThe resulting solution was filtered
  2. temperatureto cool

Sources & evidence

ORD record
ord-e24af6f1039f48b0a6b62097407c9dbd
Source dataset
uspto-grants-1979_01
Patent number
US04133889

Reaction notes

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