Sodium Bicarbonate → sodium 6-[2-hydroxy-3-(2-propylphenoxy)propoxy]-4-oxo-4H-1-benzopyran-2-carboxylate, hemihydrate

HRID 2163394Notes

Reaction equation

HRID 2163394 reaction equation
[OH:1][CH:2]([CH2:19][O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[CH2:27][CH2:28][CH3:29])[CH2:3][O:4][C:5]1[CH:6]=[CH:7][C:8]2[O:13][C:12]([C:14]([OH:16])=[O:15])=[CH:11][C:10](=[O:17])[C:9]=2[CH:18]=1.C(=O)(O)[O-].[Na+:34]>O>[OH2:1].[OH:1][CH:2]([CH2:19][O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[CH2:27][CH2:28][CH3:29])[CH2:3][O:4][C:5]1[CH:6]=[CH:7][C:8]2[O:13][C:12]([C:14]([O-:16])=[O:15])=[CH:11][C:10](=[O:17])[C:9]=2[CH:18]=1.[Na+:34].[Na+:34].[OH:1][CH:2]([CH2:19][O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[CH2:27][CH2:28][CH3:29])[CH2:3][O:4][C:5]1[CH:6]=[CH:7][C:8]2[O:13][C:12]([C:14]([O-:16])=[O:15])=[CH:11][C:10](=[O:17])[C:9]=2[CH:18]=1

Participants

4

Reactant 2

HCID 516892Sodium BicarbonateHCID 130909986-[2-hydroxy-3-(2-propylphenoxy)propoxy]-4-oxo-4H-1-benzopyran-2-carboxylic acid

Product 1

HCID 131710632sodium 6-[2-hydroxy-3-(2-propylphenoxy)propoxy]-4-oxo-4H-1-benzopyran-2-carboxylate, hemihydrate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 7.31 parts of 6-[2-hydroxy-3-(2-propylphenoxy)propoxy]-4-oxo-4H-1-benzopyran-2-carboxylic acid and 1.54 parts of sodium bicarbonate in 100 parts of water, was heated to effect solution. The solution was filtered and freeze dried to yield 7.5 parts of sodium 6-[2-hydroxy-3-(2-propylphenoxy)propoxy]-4-oxo-4H-1-benzopyran-2-carboxylate, hemihydrate.

Workup

  1. temperaturewas heated
  2. filtrationThe solution was filtered
  3. customfreeze dried

Sources & evidence

ORD record
ord-94b9e81f714740aca55764a95ee44e46
Source dataset
uspto-grants-1979_01
Patent number
US04133889

Reaction notes

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