Sodium Chloride → HCID 86736247, compound

HRID 2163488Notes

Reaction equation

HRID 2163488 reaction equation
[Cl-:1].[Na+:2].[CH2:3]([OH:14])[C@H:4]([C@H:6]([C@@H:8]([C@@H:10]([CH2:12][OH:13])[OH:11])[OH:9])[OH:7])[OH:5]>O>[Cl-:1].[Na+:2].[CH2:12]([OH:13])[C@H:10]([C@H:8]([C@@H:6]([C@@H:4]([CH2:3][OH:14])[OH:5])[OH:7])[OH:9])[OH:11]

Participants

4

Reactant 2

HCID 5234Sodium ChlorideHCID 6251Mannitol

Product 1

HCID 86736247HCID 86736247, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

10 parts by weight sodium chloride, 7.5 parts by weight mannitol, 8.0 parts by weight Polywax 5/6000, 2.5 parts by weight Kollidon VA 64 and 2.0 parts by weight sodium alginate are dissolved in warm water and sprayed in the form of a 30% solution, at a pressure of 3.0 atmospheres, through an injection needle (No. 12) into liquid nitrogen. The frozen, readily flowable granulate obtained, with a water content of 70% by weight, is tabletted in the form of ice at -20 to -25° C in a pre-cooled tabletting press. The granulate can be pressed without any melting effect or sticking taking place. The tablets obtained are dried in a desiccator over a drying agent or by lyophilization.

Workup

  1. customis tabletted in the form of ice at -20 to -25° C in a pre-cooled
  2. customThe tablets obtained
  3. customare dried in a desiccator over a drying agent or by lyophilization

Sources & evidence

ORD record
ord-28baaeb8cdf34edc95689ac28b28c04a
Source dataset
uspto-grants-1979_01
Patent number
US04134943

Reaction notes

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