HRID2163531

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID200274

未命名化合物

HCID21584188

Chloroform methanol

C2H5Cl3O

HCID22752785

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(CCN(CCCn2nc(C)c3cc(OC)c(OC)cc3c2=O)Cc2ccccc2)cc1OC

HCID22752795

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID7964

Chlorobenzene

C6H5Cl

PROCEDURE

实验过程

1-[4-Methyl-6,7-dimethoxy-1(2H)-phthalazinone-2-yl]-3-[N-benzyl-N-(2-(3,4-dimethoxy-phenyl)-ethyl)-amino]propane was prepared analogous to Example 1 (a) by reaction of 1-[4-methyl-6,7-dimethoxy-1(2H)-phthalazinone-2-yl]-3-chloro-propane with N-(3,4-dimethoxy-phenylethyl)-N-benzylamine in chlorobenzene. Rf -value (chloroform/methanol = 9/1) : 0.9.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-77b6007982e24dbf8be905ca590c24d7
来源数据集: uspto-grants-1979_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04134980
来源说明: uspto-grants-1979_01

反应 SMILES

[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:14][CH3:15])=[C:9]([O:12][CH3:13])[CH:10]=2)[C:5](=[O:16])[N:4]([CH2:17][CH2:18][CH2:19]Cl)[N:3]=1.[CH3:21][O:22][C:23]1[CH:24]=[C:25]([CH2:31][CH2:32][NH:33][CH2:34][C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)[CH:26]=[CH:27][C:28]=1[O:29][CH3:30].C(Cl)(Cl)Cl.CO>ClC1C=CC=CC=1>[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:14][CH3:15])=[C:9]([O:12][CH3:13])[CH:10]=2)[C:5](=[O:16])[N:4]([CH2:17][CH2:18][CH2:19][N:33]([CH2:34][C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)[CH2:32][CH2:31][C:25]2[CH:26]=[CH:27][C:28]([O:29][CH3:30])=[C:23]([O:22][CH3:21])[CH:24]=2)[N:3]=1