N-Methylhomoveratrylamine → HCID 12512897, compound

HRID 2163533Notes

Reaction equation

HRID 2163533 reaction equation
[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]3[O:15][CH2:14][CH2:13][O:12][C:9]=3[CH:10]=2)C(=O)N(CCCCl)N=1.COC1C=[C:25]([CH2:31][CH2:32][NH:33][CH3:34])C=CC=1OC.C(Cl)(Cl)Cl.CO>ClC1C=CC=CC=1>[CH3:34][N:33]([CH2:32][CH2:31][CH3:25])[CH2:1][CH2:2][C:11]1[CH:6]=[CH:7][C:8]([O:15][CH3:14])=[C:9]([O:12][CH3:13])[CH:10]=1

Participants

5

Reactant 3

HCID 77039N-MethylhomoveratrylamineHCID 21584188Chloroform methanolHCID 22752790HCID 22752790, compound

Product 1

HCID 12512897HCID 12512897, compound

Reagents, catalysts & solvents 1

HCID 7964ChlorobenzeneSolvent

Procedure

1-4-Methyl-6,7-ethylenedioxy-1(2H)-phthalazinone-2-yl]-3-[N-methyl-N-(2-(3,4-dimethoxy-phenyl)-ethyl)-amino]-propane was prepared analogous to Example 1 (b) by reaction of 1-[4-methyl-6,7-ethylenedioxy-1(2H)-phthalazinone-2-yl]-3-chloro-propane with N-(3,4-dimethoxy-phenylethyl)-N-methyl-amine in chlorobenzene. Yellow oil. Rf -value (chloroform/methanol = 9/1) : 0.7.

Sources & evidence

ORD record
ord-9177574aefa443b6b324471ce5e3e42e
Source dataset
uspto-grants-1979_01
Patent number
US04134980

Reaction notes

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