HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorobenzene → 1-(6,7-dimethoxy-4(3H)-quinazolinone-3-yl)-2-[N-methyl-N-(2-(3,4-dimethoxy-phenyl)-ethyl)-amino]-ethane hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorobenzene | HCID 7964 | — |
| Reactant | N-Methylhomoveratrylamine | HCID 77039 | — |
| Reactant | 1-(6,7-dimethoxy-4(3H)-quinazolinone-3-yl)-2-bromoethane | HCID 22752784 | — |
| Product | 1-(6,7-dimethoxy-4(3H)-quinazolinone-3-yl)-2-[N-methyl-N-(2-(3,4-dimethoxy-phenyl)-ethyl)-amino]-ethane hydrochloride | HCID 22752802 | — |
Reaction Steps
1-(6,7-dimethoxy-4(3H)-quinazolinone-3-yl)-2-[N-methyl-N-(2-(3,4-dimethoxy-phenyl)-ethyl)-amino]-ethane hydrochloride was prepared analogous to Example 1 (b) by reaction of 1-(6,7-dimethoxy-4(3H)-quinazolinone-3-yl)-2-bromoethane with N-(3,4-dimethoxy-phenyl ethyl)-N-methyl amine in chlorobenzene. M.p.: 205 - 208° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04134980 |
| Source dataset | uspto-grants-1979_01 |
| ORD ID | ord-bc8cecd0257c4fa6936fbe955f2272b2 |
| Source note | uspto-grants-1979_01 |