Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2163536Generated: October 26, 2026

1-Bromo-3-chloropropane → 3-(3-chloropropyl)-6,7-dimethoxy-4(3H)-quinazolinone

https://huagongshe.com/reaction/2163536

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-3-chloropropaneHCID 8006—
ReactantChloroform methanolHCID 21584188—
Reactant6,7-Dimethoxy-3H-quinazolin-4-oneHCID 135495016—
SolventDimethylformamideHCID 6228—
Product3-(3-chloropropyl)-6,7-dimethoxy-4(3H)-quinazolinoneHCID 22326631—

Reaction Steps

1-(6,7-Dimethoxy-4-(3H)-quinazolinone-3-yl)-3-chloro-propane was prepared analogous to Example 1 (a) by reaction of 6,7-dimethoxy-4(3H)-quinazolinone with 1-bromo-3-chloro-propane in dimethyl-formamide. Rf -value (chloroform/methanol = 19/1) : 0.75.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04134980
Source datasetuspto-grants-1979_01
ORD IDord-fe7681eaeecc473c830bec2004890d40
Source noteuspto-grants-1979_01