3-Chloro-6-(methylthio)pyridazine → HCID 178503271, Verbindung

Beteiligte Stoffe

Reaktionsschritte

A solution of 96 g (0.6 mol) of 3-chloro-6-methylthiopyridazine and 98.4 g (1.2 mols) of sodium acetate in 500 ml of glacial acetic acid was boiled for 2 hours under reflux. The solvent was then distilled off in vacuo, the residue was triturated with water and the reaction product was filtered off. In this way, 55.8 g (65% of theory) of 3-hydroxy-6-methylthiopyridazine were obtained in the form of a beige powder of melting point 119° C.

Herkunft & Nachweise