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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2163681Generated: October 26, 2026

Methanol → Methyl 2-(phenethylhydrazono)-propionate

https://huagongshe.com/reaction/2163681

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantMethyl pyruvateHCID 11748—
ReactantPhenelzine hydrochlorideHCID 154983—
SolventWaterHCID 962—
ProductMethyl 2-(phenethylhydrazono)-propionateHCID 73996985—

Reaction Conditions

Temperature0 °C

Reaction Steps

3.6 g. Phenethylhydrazine hydrochloride and 2.0 g. methyl pyruvate are dissolved in 20 ml. methanol and left to stand at ambient temperature for 30 minutes, followed by cooling to 0° C., whereafter 30 ml. water are added thereto. 2.8 g. (61% of theory) methyl 2-(phenethylhydrazono)-propionate crystallizes out; m.p. 59°-60° C. (decomp.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04136196
Source datasetuspto-grants-1979_01
ORD IDord-fa7788d78add487a96641939cd1fb69b
Source noteuspto-grants-1979_01