HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-tert-Butylbenzenesulfonamide → N-[4-(hexadecylamino)benzoyl]-4-t-butylbenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-tert-Butylbenzenesulfonamide | HCID 222872 | — |
| Reactant | 4-Hexadecylaminobenzoyl chloride hydrochloride | HCID 13255322 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | N-[4-(hexadecylamino)benzoyl]-4-t-butylbenzenesulfonamide | HCID 20437349 | — |
Reaction Steps
A solution of 21.1 g. of 4-(hexadecylamino)benzoyl chloride hydrochloride and 10.8 g. of p-tert-butylbenzenesulfonamide in 250 ml. of pyridine was stirred under reflux for 2 hours and evaporated. The residue was partitioned between 1N hydrochloric acid and CH2Cl2 and the organic layer was separated, washed with water, dried (MgSO4), and evaporated. Crystallization of the residual glass from CH2Cl2 hexane afforded a white solid, melting point 173°-176° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04136256 |
| Source dataset | uspto-grants-1979_01 |
| ORD ID | ord-f5471b222d6e40188886a9c207516c5f |
| Source note | uspto-grants-1979_01 |