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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2163796Generated: November 1, 2026

Piperazine → 1,4-Bis(chloroacetyl)piperazine

https://huagongshe.com/reaction/2163796

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazineHCID 4837—
ReactantChloroacetyl chlorideHCID 6577—
Product1,4-Bis(chloroacetyl)piperazineHCID 237575—

Reaction Steps

By reacting 8.6 g of piperazine with 23 g of chloroacetic chloride in the same manner as described in Synthesis Example 1, 36 g of crystals of the title compound were obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04137082
Source datasetuspto-grants-1979_01
ORD IDord-37bf63610eff42939a8e27499376e4fd
Source noteuspto-grants-1979_01