HuagongsheHuagongshe Chemistry Print Report · For research reference only
3'-Aminoacetophenone → HCID 2555322, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3'-Aminoacetophenone | HCID 7417 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-Methylisoxazole-3-carbonyl chloride | HCID 2736894 | — |
| Solvent | Acetone | HCID 180 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 2555322 | HCID 2555322 | — |
Reaction Steps
A solution of 5-methyl-3-isoxazolecarbonyl chloride (14.5 g) in acetone (30 ml) was added to a solution of m-aminoacetophenone (13.8 g) in acetone (280 ml) in the presence of anhydrous potassium carbonate (21.0 g). The mixture was stirred for 1/2hour, and then diluted with water. The precipitated product was filtered, washed with water and dried. Yield = 20.5 g (83%), m.p. 188°-190°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04137321 |
| Source dataset | uspto-grants-1979_01 |
| ORD ID | ord-d98adba4e0404f57b20cf63f0058ff24 |
| Source note | uspto-grants-1979_01 |