2-Amino-4-methylpyridine → HCID 54684989, compound

HRID 2164093Notes

Reaction equation

HRID 2164093 reaction equation
[CH3:1][N:2]1[C:15]([C:16]([O:18]C)=O)=[C:14]([OH:20])[C:5]2[N:6]([CH3:13])[C:7]3[CH:8]=[CH:9][CH:10]=[CH:11][C:12]=3[C:4]=2[S:3]1(=[O:22])=[O:21].[NH2:23][C:24]1[CH:29]=[C:28]([CH3:30])[CH:27]=[CH:26][N:25]=1>>[CH3:1][N:2]1[C:15]([C:16]([NH:23][C:24]2[CH:29]=[C:28]([CH3:30])[CH:27]=[CH:26][N:25]=2)=[O:18])=[C:14]([OH:20])[C:5]2[N:6]([CH3:13])[C:7]3[CH:8]=[CH:9][CH:10]=[CH:11][C:12]=3[C:4]=2[S:3]1(=[O:21])=[O:22]

Participants

3

Reactant 2

HCID 15332-Amino-4-methylpyridineHCID 54684931HCID 54684931, compound

Product 1

HCID 54684989HCID 54684989, compoundYield 91%

Procedure

2,5-Dihydro-2,5-dimethyl-4-hydroxy-N-(4-methyl-2-pyridyl)-1,2-thiazino[5,6-b]indole-3-carboxamide-1,1-dioxide was prepared analogous to Example 6 from methyl 2,5-dihydro-2,5-dimethyl-4-hydroxy-1,2-thiazino[5,6-b]indole-3-carboxylate-1,1-dioxide and 2-amino-4-methyl-pyridine with a yield of 91% of theory; M.p.: 250°-251° C. (decomposition).

Sources & evidence

ORD record
ord-858bde7d549f4f57bf9dfaffc0861c3f
Source dataset
uspto-grants-1979_01
Patent number
US04137313

Reaction notes

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