HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorotrimethylsilane → HCID 22750285, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorotrimethylsilane | HCID 6397 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 22750313 | HCID 22750313 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 22750285 | HCID 22750285 | — |
Reaction Steps
From 5.0 g. of 6-[4-(methylaminosulfonyl)phenyl]-1,2-dihydro-2-oxonicotinic acid in 250 ml. of tetrahydrofuran, 2.26 ml. of triethylamine, 2.05 ml. of trimethylsilyl chloride and 2.33 ml. of thionyl chloride, following the procedure of a) above, there is obtained 6-[4-(methylaminosulfonyl)phenyl]-1,2-dihydro-2-oxonicotinyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04137408 |
| Source dataset | uspto-grants-1979_01 |
| ORD ID | ord-9eabe03ad0944e3484651569b7c6a0d0 |
| Source note | uspto-grants-1979_01 |