Ethanol → HCID 54210358, compound

HRID 2164192Notes

Reaction equation

HRID 2164192 reaction equation
[Na].C(O)C.[CH2:5]([C:7]1[CH:12]=[CH:11][C:10]([SH:13])=[CH:9][CH:8]=1)[CH3:6].Br[CH:15]([CH2:17][CH2:18][CH2:19][C:20]([O:23][CH3:24])([CH3:22])[CH3:21])[CH3:16]>O>[CH2:5]([C:7]1[CH:12]=[CH:11][C:10]([S:13][CH:15]([CH3:16])[CH2:17][CH2:18][CH2:19][C:20]([O:23][CH3:24])([CH3:22])[CH3:21])=[CH:9][CH:8]=1)[CH3:6]

Participants

6

Reactant 4

HCID 702EthanolHCID 27589144-EthylthiophenolHCID 5360545SodiumHCID 22749821HCID 22749821, compound

Product 1

HCID 54210358HCID 54210358, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To 3.5 g. of sodium in 150 ml. of ethanol is added 18.8 g. of p-ethylphenyl mercaptan. The mixture is stirred for about 40 minutes and then 30 g. of 2-bromo-6-methoxy-6-methylheptane is added. The reaction mixture is heated under reflux for about 35 minutes, allowed to cool and then diluted with water. The reaction is worked up by extraction with ether, washing with water and drying over magnesium sulfate to yield 5-methoxy-1,5-dimethylhexyl p-ethylphenyl sulfide which can be purified by chromatography. ##STR15##

Workup

  1. temperatureThe reaction mixture is heated
  2. temperatureunder reflux for about 35 minutes
  3. temperatureto cool
  4. extractionThe reaction is worked up by extraction with ether
  5. washwashing with water
  6. dry with materialdrying over magnesium sulfate

Sources & evidence

ORD record
ord-24fcc54af65146f0ac12d22ae2f49514
Source dataset
uspto-grants-1979_01
Patent number
US04137273

Reaction notes

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