Pyridine → HCID 13455393, compound

Participants

Reaction Steps

A 50-g portion of 2,4-dichloroquinazoline was added to 500 ml of pyridine at ambient temperature. The reaction was stirred overnight under a calcium sulfate drying tube, chilled and filtered. The solid was rinsed thoroughly with pyridine and dried in vacuo giving 65 g of solid 1-(2-chloroquinazoline-4-yl)pyridinium chloride (m.p. 105°-107° C.; mixture melting point with 2,4-dichloroquinazoline 80°-87° C.).

Provenance & Evidence