HCID 13455393, compound → HCID 13455395, compound

HRID 2164198Notes

Reaction equation

HRID 2164198 reaction equation
[Cl-:1].[Cl:2][C:3]1[N:12]=[C:11]([N+:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1>N1C=CC=CC=1>[Cl-:2].[Cl-:1].[N:4]1[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[C:11]([N+:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[N:12][C:3]=1[N+:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 1

HCID 13455393HCID 13455393, compound

Product 1

HCID 13455395HCID 13455395, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

A 10-g portion of 1-(2-chloroquinazoline-4-yl)pyridinium chloride was added to 100 ml of pyridine under a calcium sulfate drying tube, refluxed 11/2 hours, then allowed to stir 3 days. The reaction was filtered and the solid was rinsed with pyridine, then ether, and dried in vacuo giving 10.4 g of 1,1'-(2,4-quinazolinediyl)bis[pyridinium] dichloride (m.p. 156°-162° C.).

Workup

  1. temperaturerefluxed 11/2 hours
  2. filtrationThe reaction was filtered
  3. washthe solid was rinsed with pyridine
  4. dry with materialether, and dried in vacuo

Sources & evidence

ORD record
ord-ce3b7627b04c4a089afe2e649f2f5936
Source dataset
uspto-grants-1985_03
Patent number
US04502880

Reaction notes

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