Chlorine → HCID 13394256, compound

HRID 2164261Notes

Reaction equation

HRID 2164261 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:10]=C[NH:12][C:13]=2[C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=2)=[CH:5][CH:4]=1.ClCl.[CH:24]([Cl:27])(Cl)[Cl:25].CO.C(O)(=O)C>C(Cl)(Cl)(Cl)Cl>[ClH:25].[Cl:27][C:24]1[NH:10][C:9]([C:6]2[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)=[C:13]([C:14]2[CH:15]=[CH:16][C:17]([O:20][CH3:21])=[CH:18][CH:19]=2)[N:12]=1

Participants

5

Reactant 3

HCID 24526ChlorineHCID 14100143HCID 14100143, compoundHCID 21866353chloroform methanol HOAc

Product 1

HCID 13394256HCID 13394256, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

A suspension of 4,5-bis(4-methoxyphenyl)-1H-imidazole (10.0 g, 0.036 mol) in 200 ml of carbon tetrachloride was treated with chlorine until no starting material was evidenced by tlc (chloroform-methanol-acetic acid, 17:1:2). The resulting solid was collected by filtration, washed with carbon tetrachloride, and dried in vacuo to yield 12.5 g (100%) of the title compound, m.p. 129°-132° (dec.).

Workup

  1. filtrationThe resulting solid was collected by filtration
  2. washwashed with carbon tetrachloride
  3. customdried in vacuo

Sources & evidence

ORD record
ord-32d353687a154351a6f5cf6d69ee531b
Source dataset
uspto-grants-1985_03
Patent number
US04503065

Reaction notes

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