Water → HCID 86739961, compound

Participants

Reaction Steps

1,3-dimethoxy-2-(2',3'-dihydroxypropyl)-amino-propane (96.6 g, 0.5 moles) in 1000 ml of 20% hydrochloric acid is refluxed for 65 hours and subsequently worked up according to the method described in Example 2 B. The readily water soluble 1,3-dihydroxy-2-(2',3'-dihydroxypropyl)-amino-propane, which boils at about 155° C. at 0.05 torr, is obtained in a yield of 64.4 g, corresponding to 78% of the theoretical.

Provenance & Evidence