Water → HCID 86739961, compound

HRID 2164344Notes

Reaction equation

HRID 2164344 reaction equation
C[O:2][CH:3]([NH2:13])[CH:4]([CH2:8][CH:9]([OH:12])[CH2:10][OH:11])[CH2:5][O:6]C.O>Cl>[OH:2][CH:3]([NH2:13])[CH:4]([CH2:8][CH:9]([OH:12])[CH2:10][OH:11])[CH2:5][OH:6]

Participants

4

Reactant 2

HCID 962WaterHCID 86739962HCID 86739962, compound

Product 1

HCID 86739961HCID 86739961, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

1,3-dimethoxy-2-(2',3'-dihydroxypropyl)-amino-propane (96.6 g, 0.5 moles) in 1000 ml of 20% hydrochloric acid is refluxed for 65 hours and subsequently worked up according to the method described in Example 2 B. The readily water soluble 1,3-dihydroxy-2-(2',3'-dihydroxypropyl)-amino-propane, which boils at about 155° C. at 0.05 torr, is obtained in a yield of 64.4 g, corresponding to 78% of the theoretical.

Sources & evidence

ORD record
ord-f9390bde30a840e8bf94afc80c63bb59
Source dataset
uspto-grants-1985_03
Patent number
US04503252

Reaction notes

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