2-Nitrophenol → 1-[2-(2-Chloroethoxy)ethoxy]-2-nitrobenzene

HRID 2164376Notes

Reaction equation

CO[C:3]1[CH:4]=[CH:5][C:6]([N+:16]([O-:18])=[O:17])=[C:7]([O:9][CH2:10][CH2:11][O:12][CH2:13][CH2:14][Cl:15])[CH:8]=1.[Na].[N+](C1C=CC=CC=1O)([O-])=O.COC1C=CC([N+]([O-])=O)=C(O)C=1>>[N+:16]([C:6]1[CH:5]=[CH:4][CH:3]=[CH:8][C:7]=1[O:9][CH2:10][CH2:11][O:12][CH2:13][CH2:14][Cl:15])([O-:18])=[O:17]

Participants

Reactant 4

HCID 69472-Nitrophenol

HCID 2196355-Methoxy-2-nitrophenol

HCID 5360545Sodium

HCID 20405423HCID 20405423, compound

Product 1

HCID 204054271-[2-(2-Chloroethoxy)ethoxy]-2-nitrobenzene

Procedure

This compound was prepared in a manner analogous to the preparation of 5-methoxy-2-nitro-[2-(2-chloroethoxy)ethoxy]benzene for crown ether XIX, except that the sodium salt of o-nitrophenol was used instead of the sodium salt of 5-methoxy-2-nitrophenol.

Sources & evidence

ORD record: ord-e0dfb138865d4946b8ff19d28c2d5609
Source dataset: uspto-grants-1985_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04504368

Reaction notes

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