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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2164445Generated: October 30, 2026

2-Amino-6-fluorobenzonitrile → 2-Amino-6-(methylamino)benzonitrile

https://huagongshe.com/reaction/2164445

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-6-fluorobenzonitrileHCID 522659—
ReactantMethylammoniumacetatHCID 14420923—
SolventN-MethylformamideHCID 31254—
Product2-Amino-6-(methylamino)benzonitrileHCID 12715717—

Reaction Steps

The title compound is prepared by heating a 10 molar excess of methylammonium acetate and 2-amino-6-fluorobenzonitrile in N-methyl formamide at 140° C. for 5 hrs.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04504660
Source datasetuspto-grants-1985_03
ORD IDord-2da8c8d506164326b39e6dbd2c51eba6
Source noteuspto-grants-1985_03