HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2-Fluoro-6-(methylamino)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 2,6-Difluorobenzonitrile | HCID 74695 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Fluoro-6-(methylamino)benzonitrile | HCID 13469797 | — |
Reaction Steps
2,6-Difluorobenzonitrile, 2.78 g (20 mmol) and 5 ml (60 mmol) of 40% aqueous methylamine in 50 ml DMF is stirred at room temperature for 1 hr., poured into water and the product is collected, 2.4 g m.p. 130°-132° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04504660 |
| Source dataset | uspto-grants-1985_03 |
| ORD ID | ord-d54ade8330034c1ab3d36e8d8ce7f104 |
| Source note | uspto-grants-1985_03 |