反应详情

L-Ala-D-Glu(OH)OBzl (1) (942 mg) was suspended in methylene chloride (40 ml), and bis(trimethylsilyl)acetamide (1.20 g) was added to the suspension under stirring. The resulting solution was treated with stearoyl chloride (900 mg) at ambient temperature and left for an hour. Evaporation of the solvent gave an oily residue which was treated with water to give white solides. The solides were collected by filtration, washed with water and dried over magnesium sulfate to give stearoyl-L-Ala-D-Glu(OH)OBzl (2) (1.60 g).

1. waitleft for an hour
2. customEvaporation of the solvent
3. customgave an oily residue which
4. customto give white solides
5. filtrationThe solides were collected by filtration
6. washwashed with water
7. dry with materialdried over magnesium sulfate