HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Aminosulfonyl)-5-chlorophthalimide → Phthalimide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Aminosulfonyl)-5-chlorophthalimide | HCID 19733 | — |
| Reactant | N-(2-Aminoethyl)piperidine | HCID 33944 | — |
| Reactant | HCID 13473187 | HCID 13473187 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Phthalimide | HCID 6809 | 71% |
Reaction Steps
6-Chloro-2,3-dihydro-2-[2-(1-piperidinyl)ethyl]-1,3-dioxo-1H-isoindole-5-sulfonamide. Reaction of a mixture of 4-chloro-5-sulfamoylphthalimide and 2-(1-piperidinyl)ethylamine according to the procedure of Example 1(a) afforded a 71% yield of the 1,3-dioxoisoindole intermediate, m.p. 200°-202° from ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04505911 |
| Source dataset | uspto-grants-1985_03 |
| ORD ID | ord-472f529083b443629aee8941f4a74366 |
| Source note | uspto-grants-1985_03 |