HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Pentanol → Phthalimide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Pentanol | HCID 6276 | — |
| Reactant | 4-(Aminosulfonyl)-5-chlorophthalimide | HCID 19733 | — |
| Product | Phthalimide | HCID 6809 | 57% |
Reaction Steps
6-Chloro-2,3-dihydro-1,3-dioxo-2-[2-[N-methyl-N-(phenylmethyl)]ethyl]-1H-isoindole-5-sulfonamide. Reaction of 4-chloro-5-sulfamoylphthalimide (9.5 g., 0.0365 mole) and 2-[N-methyl-N-(phenylmethyl)]ethylamine (6.0 g., 0.0365 mole) in 200 ml. of amyl alcohol at reflux temperature for a 24 hr. period under nitrogen according to the procedure of Example 1(a) afforded a 57% yield of the 1,3-dioxoisoindole intermediate, m.p. 182°-187° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04505911 |
| Source dataset | uspto-grants-1985_03 |
| ORD ID | ord-f497430c64b643be9ab9cda6d5ba1352 |
| Source note | uspto-grants-1985_03 |