1-Methylpiperazine → HCID 86739982, compound

HRID 2164555Notes

Reaction equation

HRID 2164555 reaction equation
[CH3:1][CH:2]([CH3:20])[CH2:3][NH:4][S:5]([C:8]1[CH:19]=[C:12]2[C:13]([O:15]C(=O)[NH:17][C:11]2=[CH:10][CH:9]=1)=O)(=[O:7])=[O:6].[CH3:21][N:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1>C(O)C>[CH3:21][N:22]1[CH2:27][CH2:26][N:25]([C:13](=[O:15])[C:12]2[C:11](=[CH:10][CH:9]=[C:8]([S:5](=[O:6])(=[O:7])[NH:4][CH2:3][CH:2]([CH3:1])[CH3:20])[CH:19]=2)[NH2:17])[CH2:24][CH2:23]1

Participants

4

Reactant 2

HCID 531671-MethylpiperazineHCID 54563094HCID 54563094, compound

Product 1

HCID 86739982HCID 86739982, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a manner analogous to that described in Example 1, the reaction of 5-[N-(2-methylpropyl)-sulfamoyl]-isatoic anhydride with 1-methylpiperazine yields 5-[N-(2-methylpropyl)-sulfamoyl]-anthranilic acid (4-methyl)-piperazide with a melting point of 162°-163° (from ethanol; melting point of the hydrochloride: 254°-255°).

Sources & evidence

ORD record
ord-bf2f852d85fd4ad697d723149c016f03
Source dataset
uspto-grants-1985_03
Patent number
US04505913

Reaction notes

Loading…