1-Methylpiperazine → HCID 86739984, compound

HRID 2164559Notes

Reaction equation

HRID 2164559 reaction equation
[CH3:1][NH:2][S:3]([C:6]1[CH:17]=[C:10]2[C:11]([O:13]C(=O)[NH:15][C:9]2=[CH:8][CH:7]=1)=O)(=[O:5])=[O:4].[CH3:18][N:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1>>[CH3:18][N:19]1[CH2:24][CH2:23][N:22]([C:11](=[O:13])[C:10]2[C:9](=[CH:8][CH:7]=[C:6]([S:3](=[O:4])(=[O:5])[NH:2][CH3:1])[CH:17]=2)[NH2:15])[CH2:21][CH2:20]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 54433427HCID 54433427, compound

Product 1

HCID 86739984HCID 86739984, compound

Procedure

In a manner analogous to that described in Example 1, the reaction of 5-(N-methylsulfamoyl)-isatoic anhydride with 1-methylpiperazine yields 5-(N-methylsulfamoyl)-anthranilic acid (4-methyl)-piperazide in the form of an oil (melting point of the methanesulfonate: 120°-123°).

Sources & evidence

ORD record
ord-3f3ce968e924408f973aef016256c644
Source dataset
uspto-grants-1985_03
Patent number
US04505913

Reaction notes

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