1-Methylpiperazine → HCID 86739985, compound

HRID 2164561Notes

Reaction equation

HRID 2164561 reaction equation
[CH2:1]([NH:3][S:4]([C:7]1[CH:18]=[C:11]2[C:12]([O:14]C(=O)[NH:16][C:10]2=[CH:9][CH:8]=1)=O)(=[O:6])=[O:5])[CH3:2].[CH3:19][N:20]1[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]1>CC(C)=O.C(O)C>[CH3:19][N:20]1[CH2:25][CH2:24][N:23]([C:12](=[O:14])[C:11]2[C:10](=[CH:9][CH:8]=[C:7]([S:4](=[O:5])(=[O:6])[NH:3][CH2:1][CH3:2])[CH:18]=2)[NH2:16])[CH2:22][CH2:21]1

Participants

4

Reactant 2

HCID 531671-MethylpiperazineHCID 53692218HCID 53692218, compound

Product 1

HCID 86739985HCID 86739985, compound

Reagents, catalysts & solvents 1

HCID 21889777Acetone ethanolSolvent

Procedure

In a manner analogous to that described in Example 1, the reaction of 5-(N-ethylsulfamoyl)-isatoic anhydride with 1-methylpiperazine yields 5-(N-ethylsulfamoyl)-anthranilic acid (4-methyl)-piperazide with a melting point of 175°-177° (from acetone/ethanol).

Sources & evidence

ORD record
ord-afcd63b9e63142128a717f0db27162cc
Source dataset
uspto-grants-1985_03
Patent number
US04505913

Reaction notes

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