Benzoic acid, 2-chloro-5-(chlorosulfonyl)- → 2-Chloro-5-(ethylsulfamoyl)benzoic acid

Participants

Reaction Steps

5-(N-Ethylsulfamoyl)-isatoic anhydride, which is to be used as the starting material, can be obtained, for example, in a manner analogous to that described in Example 1, using 2-chloro-5-chlorosulfonyl-benzoic acid as the starting material, the product being obtained via 5-(N-ethylsulfamoyl)-2-chloro-benzoic acid with a melting point of 186°-190° and 5-(N-ethylsulfamoyl)-anthranilic acid with a melting point of 190°-192°; the product melts at 253°-255°.

Provenance & Evidence