4-Nitrophenol → HCID 13384709, compound

HRID 2164569Notes

Reaction equation

HRID 2164569 reaction equation
[CH2:1]([O:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][C:12]([OH:14])=[O:13])=[CH:7][C:6]=1[Cl:15])[CH:2]=[CH2:3].[CH:16]1[C:21]([N+:22]([O-:24])=[O:23])=[CH:20][CH:19]=[C:18](O)[CH:17]=1.C1CCC(N=C=NC2CCCCC2)CC1>O1CCCC1.C(Cl)(Cl)Cl>[N+:22]([C:21]1[CH:16]=[CH:17][C:18]([O:13][C:12](=[O:14])[CH2:11][C:8]2[CH:9]=[CH:10][C:5]([O:4][CH2:1][CH:2]=[CH2:3])=[C:6]([Cl:15])[CH:7]=2)=[CH:19][CH:20]=1)([O-:24])=[O:23]

Participants

6

Reactant 3

HCID 9804-NitrophenolHCID 10868DicyclohexylcarbodiimideHCID 30951Alclofenac

Product 1

HCID 13384709HCID 13384709, compound

Reagents, catalysts & solvents 2

HCID 6212ChloroformSolventHCID 8028TetrahydrofuranSolvent

Procedure

4-Allyloxy-3-chloro-phenylacetic acid (4.3 g) was dissolved in dry tetrahydrofuran (20 ml). To the solution was added p-nitrophenol (2.28 g) in dry chloroform (30 ml). DCC (4.1 g) was then added and the whole was then stirred at room temperature overnight.

Sources & evidence

ORD record
ord-01cd69f52ce448fb9e6e993d379c161c
Source dataset
uspto-grants-1985_03
Patent number
US04505898

Reaction notes

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